ABSTRACT
OBJECTIVE: To determine the prevalence of depression in Filipino adult patients with type 2 diabetes mellitus (DM) and the risk factors associated in its development.METHODS: This is a prospective cross-sectional study. Adult patients (age 19 and above) with type 2 DM being seen at the outpatient department of the Makati Medical Center from January to March 2015 were included, taking into account the following: age, gender, marital status, body mass index, waist circumference, blood pressure, duration of diabetes, presence of other co-morbid illnesses, pill burden, insulin use, educational attainment, employment status, family income, and glycemic status. They were then screened for depression using the standardized PHQ-9 questionnaire. Bivariate analyses through Chi-square Test (for categorical variables) and Analysis of Variance (for interval/ratio variables) were used to determine which among the risk factors are significant for the development of depression. Significant risk factors were treated for multivariate and univariate analyses through ordinal logistic regression.RESULTS: A total of 110 adult patients with type 2 DM were enrolled in this study. There were no drop-outs. Sixty-nine percent of the patients had none to minimal depression, 24% had mild depression, and 7% had moderate depression. None of the patients had depression that warranted anti-depressants or psychotherapy. After step-wise analysis, increased BMI, elevated diastolic blood pressure and uncontrolled blood sugar were found to be associated with higher PHQ-9 scores while unemployment was associated with decreased PHQ-9 score.CONCLUSION: The prevalence of depression among Filipino type 2 diabetic patients is higher than in non-diabetic patients. Being obese, having an elevated diastolic blood pressure, and the presence of uncontrolled blood sugar were significant predictors and were associated with an increased likelihood of developing major depressive disorder. Being unemployed appears to have the opposite effect.
Subject(s)
Humans , Male , Female , Aged , Middle Aged , Adult , Blood Glucose , Diabetes Mellitus, Type 2 , Depression , Depressive Disorder, Major , Insulin , Body Mass Index , Waist Circumference , PsychotherapyABSTRACT
OBJECTIVES: The study examined the prevalence of elevated thyroid stimulating hormone (TSH) and its association with dyslipidemia and non-alcoholic fatty liver disease (NAFLD) among Filipino adults undergoing executive check-up. METHODS: Clinical characteristics such as age, vital signs, anthropometrics, FBS, lipid profile, liver function tests, TSH and hepatobiliary ultrasound were reviewed from the charts of 580 patients to determine the prevalence of elevated TSH, NAFLD, and dyslipidemia. Binary logistic regression analysis was performed to determine association between TSH levels, NAFLD, and dyslipidemia. RESULTS: The prevalence of elevated TSH was 3.10%. Patients with increased total cholesterol was approximately 4.18 times as likely (95% CI 1.20 to 14.61%, p = 0.025) to have elevated TSH. However, after adjusting for age and sex, we had insufficient evidence to demonstrate an association between NAFLD and lipid levels with elevated TSH levels. CONCLUSION: The prevalence of elevated TSH in this group of patients from a highly urbanized area was 3.1%. We had insufficient evidence to demonstrate an association between NAFLD, lipid levels, and elevated TSH levels after adjusting for age and sex.
Subject(s)
Humans , Male , Female , Middle Aged , Thyrotropin , Non-alcoholic Fatty Liver Disease , Prevalence , Liver Function Tests , Dyslipidemias , Hypercholesterolemia , Digestive System , Cholesterol , LipidsABSTRACT
OBJECTIVE: To determine the relationship between hypothyroidism and color vision deficiency among Filipinos ages 20-60 yearsDESIGN AND METHODS: A cross-sectional study was performed on 91 biochemically hypothyroid and euthyroid patients seen at the Makati Medical Center from July to December 2013. All subjects underwent the Ishihara color test, followed by the Farnsworth-Munsell D15 test if this was positive. The patient who tested positive in the Farnsworth-Munsell D15 test was referred to an ophthalmologist to rule out any anatomic problem, and was excluded from the study if found to have any. Fisher's exact test assessed the significant correlation between hypothyroidism and color vision deficiency. A p-value less than 0.05 was considered significant.RESULTS: Of the 91 patients that were included in the study, the average age was 42 years, majority (87%) were females, and 41% were biochemically hypothyroid. All euthyroid patients (100%) had normal color vision, while one hypothyroid patient (3.0%) tested positive for color vision deficiency (p-value 0.407).CONCLUSION: Based on this study, the hypothyroid state of the patients had no effect on their color vision, unlike those seen in rodents, probably because mature human cones are not as easily affected by changes in thyroid hormone levels.